Disease: Inherited neuropathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WASHC5 Q12768 WASH complex subunit 5 Transporter 8.3E-18 0.572 0.615
WARS1 P23381 tryptophanyl-tRNA synthetase 1 Enzyme 0.30 0.650 0.654
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
SPTLC1 O15269 serine palmitoyltransferase long chain base subunit 1 Enzyme 4.2E-11 0.650 0.538
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SH3TC2 Q8TF17 SH3 domain and tetratricopeptide repeats 2 8.3E-16 0.666 0.385
SBF2 Q86WG5 SET binding factor 2 Enzyme 6.4E-10 0.619 0.577
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654
RNMT O43148 RNA guanine-7 methyltransferase 5.7E-05 0.647 0.500
RFC1 P35251 replication factor C subunit 1 0.97 0.541 0.808
PXMP2 Q9NR77 peroxisomal membrane protein 2 Receptor 9.2E-03 0.743 0.192
PRX Q9BXM0 periaxin 2.1E-14 0.650 0.577
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
NTF3 P20783 neurotrophin 3 Signaling 0.93 0.519 0.808
NDRG1 Q92597 N-myc downstream regulated 1 Enzyme 1.1E-02 0.488 0.731
MYO1A Q9UBC5 myosin IA Cellular structure 8.9E-46 0.769 0.269
MTMR2 Q13614 myotubularin related protein 2 Enzyme 3.0E-07 0.659 0.538
MTM1 Q13496 myotubularin 1 Enzyme 1.00 0.573 0.731
MPZ P25189 myelin protein zero 0.27 0.503 0.846
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
MAD2L1BP Q15013 MAD2L1 binding protein 1.4E-08 0.623 0.577
LRIG3 Q6UXM1 leucine rich repeats and immunoglobulin like domains 3 Receptor 1.2E-09 0.743 0.231
LPAR1 Q92633 lysophosphatidic acid receptor 1 G-protein coupled receptor 0.19 0.534 0.808